Covers:

1926:

Martha Copeland

1926:

Ma Rainey

1927:

Clarence Williams

1927:

Blind Lemon Jefferson [as Black Snake Moan]

1927:

Martha Copeland [idem]

1927:

King Oliver

1959:

John Lee Hooker [as Black Snake for Riverside and crediting Blind Lemon while turning it into something all of his own]

1969:

Cuby & The Blizzards [idem on Appleknockers Flophouse]

1996:

Jimmie Dale Gilmore [as Black Snake Moan]

2007:

Samuel L. Jackson & Jason Freeman [in Craig Brewer film Black Snake Moan]