Spelled out as Ain't It A Shame on the original labels. Not to be confused with Lloyd Price's hit Ain't It A Shame ('53).
Pat Boone [n°1 US; Fats Domino's comment: "This man bought me this ring with this song"]
John Lennon [one of the first songs, if not the first song he learned to play, through his mother Julia on banjo, who probably only knew the Pat Boone hitversion]
Paul McCartney [on his Russian lp]